Sr. Manager, Upstream Marketing - Global Markets

HistoSonics is a commercial-stage medtech company advancing the Edison® System, a novel non-invasive sonic beam therapy based on histotripsy. Since receiving FDA De Novo grant for the non-invasive destruction of liver tumors in 2023, the company has progressed beyond initial market entry into commercial expansion, reimbursement momentum, and ongoing clinical and pipeline development. In addition to its current liver tumor indication, HistoSonics is pursuing future indications across multiple applications including kidney, pancreas, prostate, neuro, women’s health, and other significant underserved human health areas, to realize the broader potential histotripsy across multiple disease states and medical specialties.

We offer an exciting work culture where cutting-edge science meets real-world application, and each team member’s contribution is important to our success in ensuring our physicians and their patients get what they need most.

Location: Plymouth, MN

Travel: Up to 33% domestically and internationally 

Position Summary (Why this role matters): 

The Sr Manager, Upstream Marketing – Global Markets serves as the strategic hub connecting HistoSonics’ core functions with regional business leaders across Europe, Asia, and other OUS markets. This role partners with regional and cross-functional stakeholders to assess market opportunities, develop market-entry and go-to-market strategies, prioritize markets and product portfolios, and ensure launch readiness.

Working within a global hub-and-spoke model, this individual synthesizes global insights and global customer needs, aligns priorities, drives execution, and provides visibility into progress, risks, and readiness across the global portfolio.

Key Responsibilities (What you’ll do): 

Strategic Partnership & Program Leadership

• Serve as the primary link between Regulatory, Commercial, Clinical, Operations, and regional business leaders to ensure alignment, accountability, and execution across OUS markets.
• Partner with regional leaders to assess market opportunities and co-develop market-entry priorities, product requirements, launch plans, and resource needs.
• Facilitate cross-functional decision-making, remove barriers, and drive execution across international commercialization initiatives.
• Lead globalization operating activities, including leadership reviews, agenda development, milestone and action tracking, and prioritization activities. 

Market Development & Launch Readiness

• Partner with regional teams to develop and execute launch readiness plans for non-U.S. markets.
• Maintain launch timelines, readiness checklists, and cross-functional deliverables.
• Collaborate with downstream marketing, sales, clinical, and regulatory teams to ensure training, messaging, market activation, and operational readiness.
• Co-develop go-to-market strategies, including market segmentation, customer targeting, product portfolio prioritization, and reimbursement assessments.
• In person support for key customer, KOL, distributor, and conference engagements in priority international markets. 

Reporting, Visibility & Risk Management

• Maintain dashboards and reporting for shipments, installations, market development activities, launch readiness, and key performance indicators.
• Consolidate data and provide concise, actionable updates to leadership on progress, risks, and business performance.
• Identify, track, and communicate risks across markets and workstreams, partnering with stakeholders to develop mitigation plans.
• Maintain a global risk register and proactively escalate issues impacting timelines, commitments, or launch readiness. 

Additional Responsibilities

• Partner with regional leaders to identify new market opportunities, geographic prioritization frameworks, and product portfolio strategies.
• Co-create OUS launch strategies and market development plans that are globally aligned and regionally executable.
• Monitor competitive activity and market dynamics, translating insights into recommendations for global planning and prioritization.
• Gather region-specific customer and product requirements and communicate findings to Product Management and R&D.

 Qualifications and Skills:  

• Bachelor’s degree required; advanced degree preferred in business, marketing, life sciences, engineering, or related field.
• 8+ years of experience in global product management, program management, or commercial operations within the medical device industry.
• 5+ years of experience supporting international product launches, market development, or OUS commercial operations preferred.
• Experience working within matrixed global organizations and influencing stakeholders outside of direct reporting lines.
• Familiarity with international regulatory pathways (e.g., CE Mark, PMDA, TGA) preferred.
• Experience working with distributors in Europe and Asia-Pacific preferred.
• Strong program management, analytical, reporting, communication, and influencing skills.
• Ability to synthesize market insights, competitive intelligence, and business needs into actionable recommendations.
• Proven ability to manage multiple priorities, navigate ambiguity, identify risks, and drive outcomes.
• Proficiency in Microsoft Office; experience with project management tools such as Smartsheet, Asana, or equivalent preferred.
• Collaborative, results-oriented mindset with strong follow-through.

Travel

• Ability to travel domestically and internationally up to 33%, including overnight and multi-day trips. 

Benefits: We offer a comprehensive benefits package for full-time employees. This includes health, dental, and vision insurance, life, short-term and long-term disability insurance, 401(k), paid time off, and more.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

U.S. Work Authorization & Sponsorship: Employer will not sponsor visas for position.