Research Technologist I - Ma Lab

Performs laboratory assays and complex experiments to elucidate novel research questions. The Ma Lab studies integrin signaling in blood cells. Integrin family receptors deliver bidirectional signaling (inside-out and outside-in) across the cell plasma membrane, modulating cell adhesion, migration, proliferation, differentiation, and other functions. Integrin signaling involves a series of molecular events within cells that enable integrins to bridge the crosstalk between the extracellular milieu and cytoskeletal changes, as well as cytoplasmic signaling cascades. Integrin activation is tightly regulated by integrin cytoplasmic tail binding proteins (ICBPs). The interaction between integrins and ICBPs defines the activation states and functional activities of integrins. Dysfunction of...