Job Description
The Duke University laboratory of Dorothy Sipkins, M.D., Ph.D. is seeking a highly motivated postdoctoral associate with research interest in metastasis and the tumor microenvironment. Our group has a diverse and stimulating environment with projects in basic and translational research as well as clinical trial studies.
Research: Dissect the key signaling events that regulate tumor cell peripheral nerve invasion (PNI) in pancreatic cancer. This will include studying the role of integrin alpha-6:laminin and neurotrophin cell signaling interactions in this process. Test the efficacy of integrin alpha-6 blockade to prevent PNI and reduce tumor progression in pancreatic cancer. Analyze primary patient correlative research samples for expression of relevant signaling molecules and their association with PNI and pancreatic cancer disease progression.
Duke University is an exceptional environment for research because of its rich intellectual community and pervasive spirit of collegiality. Duke consists of 10 schools, with 6,484 undergraduate and 8,107 graduate or professional students. The resources and support for postdoctoral fellows at Duke are outstanding, with numerous professional development workshops and training opportunities. The Sipkins Lab is within the Division of Hematologic Malignancies and Cellular Therapy, a division of the Department of Medicine and part of the Duke Cancer Institute (DCI). The DCI is a single entity that integrates and aligns research and patient care with the goals of decreasing the burden of cancer and accelerating scientific progress.
This position requires a PhD in cell biology, immunology, or other relevant areas of biomedical sciences. Experience in one or more of the following areas is desirable: 1) In vivo mouse models (willingness to work with animal models is a must), 2) Immunology (flow cytometry) 3) Molecular biology techniques. The ideal candidate should be motivated, innovative, with strong problem-solving and interpersonal skills and excitement to learn new techniques.
To apply, please provide CV/biosketch, brief statement of research interests/experience, and contact information for 2-3 references.
Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.
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