Job Description
Description
- Design and execute strategies for stable cell line development using CHO cell line systems.
- Perform hands-on CHO cell line development and characterization studies, including transfection, selection, single cell subcloning, growth and productivity screening, cell banking and stability assessment of cell banks.
- Culture mammalian cells across multiple scales and formats, from 96-well plates up to large shake flasks, experience with ambr 250 and bioreactors is ideal.
- Implement high-throughput screening and automation tools for clone evaluation.
- Maintain rigorous documentation and ensure compliance with quality and regulatory standards.
- Author and review cell line development reports, summaries, and presentations.
- Present updates at client and cross-functional meetings.
- Partner with Upstream and Downstream Process Development and Analytical teams to deliver integrated solutions.
- Contribute to technology evaluations and continuous improvement initiatives for cell line workflows.
- M.S. in Cell Biology, Molecular Biology, Biochemistry, or related field.
- 2-5 years of industry experience in cell development for biologics.
- Hands-on experience with CHO cell systems, transfection methods, and clone screening for production of monoclonal antibodies, antibody-like molecules, enzymes, cytokines, bi-specifics and other recombinant molecules.
- Strong knowledge of mammalian cell culture, molecular biology techniques and bio process engineering concepts.
- Proficient in aseptic mammalian cell culture techniques.
- Familiarity with automation platforms and data analysis tools.
- Excellent problem-solving and communication skills.
Preferred Qualifications:
- Knowledge of regulatory requirements for GMP manufacturing.
- Exposure to high-throughput analytics and bioinformatics tools.
- You have a "bring it on!" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.
- Your written and verbal skills are out of this world, and you communicate with clarity and confidence.
- You have exceptional multitasking skills and an unparalleled attention to detail that ensure the smooth running of everything.
- You are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.
