Director, Real Estate

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

Madrigal Pharmaceuticals is seeking a Director, Facilities to support and advance our workplace strategy across a growing footprint. Reporting to the Executive Director of Real Estate & Facilities, this role will manage office managers and ensure that our workplaces foster efficiency, collaboration, and employee engagement.

The ideal candidate brings strong workplace operations and facilities leadership experience, combined with the ability to implement tools, systems, and programs that elevate the employee experience. This leader will also assist with contributing insights and support for strategic decision-making.

Key Responsibilities

Leadership & Team Development

• Manage and mentor office managers across US and International locations, driving consistency and excellence in workplace services.
• Cultivate a hospitality-driven, people-first workplace culture.
• Provide strong management oversight with an emphasis on developing team capability, accountability, and attention to detail.
• Partner closely with HR, IT, Finance, and other stakeholders to align workplace initiatives with company needs.

Workplace Operations & Experience

• Oversee workplace hospitality, office operations, and employee experience programs across all U.S. and international locations.
• Establish and maintain workplace standards, policies, operating procedures, and performance metrics to ensure consistent, high-quality employee experience across all locations.
• Lead initiatives that enhance workplace engagement, operational effectiveness, and organizational productivity.
• Advance workplace technologies and systems, including visitor management, space planning, and service request platforms, to streamline operations and improve service delivery.
• Oversee workplace planning and utilization systems to optimize space usage, support growth, and provide data-driven insights.
• Support the development and execution of workplace, facilities, and real estate strategies that align with organizational growth and business objectives.

Real Estate & Facilities Support

• Maintain lease documentation, critical dates, reporting, and portfolio records while supporting the Executive Director's portfolio management strategy.
• Lead day-to-day oversight and coordination of construction, relocation, and workplace projects, ensuring execution aligns with strategic direction established by the Executive Director.
• Support safe and efficient facilities operations in partnership with workplace, safety, and business stakeholders.

Financial & Vendor Management

• Partner in developing and monitoring workplace and facilities budgets.
• Manage vendor relationships for office services, workplace technologies, and facilities operations.
• Track KPIs for operational efficiency, cost control, and employee satisfaction.

Environmental Health, Safety & Ergonomics

• Develop and implement a comprehensive EHS program for corporate office operations (no lab/manufacturing scope).
• Ensure compliance with OSHA, local building codes, and other applicable regulations.
• Lead ergonomics assessments and programs to enhance employee health, safety, and comfort.
• Partner with HR and Facilities to drive workplace safety training and emergency preparedness initiatives.
• Establish metrics, audits, and continuous improvement programs for safety performance.
• Oversee sustainability and environmental initiatives aligned with corporate responsibility goals, both domestically and internationally
• Support business continuity, crisis response, and workplace resiliency planning across office locations.

Required Skills & Qualifications

• Proven leadership and management experience overseeing workplace and/or facilities teams in a global context.
• Strong background in occupancy planning, workplace utilization analysis, and implementation of space strategies.
• Demonstrated organizational excellence and attention to detail in managing systems, processes, and deliverables.
• Previous project management experience with successful execution of relocations, build outs or multi-site initiatives.
• Experience supporting real estate portfolio activities.
• Excellent communication and collaboration skills; able to work effectively across all levels of the organization.
• Ability to lift up to 50 pounds.
• Ability to work onsite, 5 days a week, in Conshohocken, PA.

Education & Experience

• Bachelor’s degree in Real Estate, Facilities Management, Business, or related field and 10+ years experience  or;
   
• HS diploma with 15+ years of progressive workplace, facilities, real estate, or related leadership experience.
• Demonstrated success implementing workplace systems and technologies that improve efficiency and employee experience.
• Ability to travel domestically and internationally up to 15–20% as business needs require.

Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands.  As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $201,000 - $246,000 per year.  We comply with all applicable minimum wage laws.

All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.  

Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws. 

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact [email protected]. 

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law. 

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established. 

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site. 

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.  

Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to [email protected].