Postdoctoral Research Associate, Department of Child Health (College of Medicine - Phoenix)

Perform independent research experiments under the direction of the Principal Investigator. Design, implement, and manage independent and collaborative research projects focused on the molecular and immunological mechanisms of pulmonary hypertension. Conduct in vivo studies, including mouse handling, chronic hypoxia/SU5416 exposure protocols, physiological assessments, and tissue harvesting. Perform in vitro experiments using endothelial, smooth muscle cell, fibroblast and immune cell models, including gene knockdown, proliferation (BrdU), migration, and angiogenesis assays. Analyze and interpret experimental data, including high-throughput datasets such as bulk and single-cell RNA sequencing, proteomics (proximity-based biotinylation, secretomics). Investigate inflammatory and immune signaling pathways, including interferon-regulated gene expression and immune cell dynamics. Maintain mouse colonies. Analyze research data and statistics. Laboratory record keeping and general laboratory activities. Participate in the acquisition of research funding by initiating and writing grant proposals. Participate or author articles in peer-reviewed journals, books or chapter publications. Participate or present at meetings and research conferences. May co-author and may co-present results with principal investigators at meetings or conferences. Assist with laboratory management including: Maintain and service laboratory equipment. Laboratory purchases and budgeting. Manage biosafety requirements. Organize laboratory and implement procedures. Coordinate with building/facilities management, gas delivery, and other key research infrastructure. Knowledge, Skills, and Abilities: Knowledge of coordinating experiments, and completing analysis, statistics, and interpretation. A strong team player. Ability to communicate in a clear, concise manner orally and in writing. Ability to participate at scientific conferences and present findings. Knowledge of grant writing and manuscript preparation. Demonstrated ability to independently develop reports and manuscripts and present findings in tabular, oral, written, and/or graphic formats.