Associate Director, Medicinal Chemistry

This position will support Supernus’ drug discovery and preclinical development efforts by contributing directly to medicinal chemistry programs focused on small molecule therapeutics for CNS disorders. This person will have a proven track record of advancing multiple compounds from lead generation through development candidate nomination, with demonstrated impact on projects reaching IND-enabling studies or beyond. This role requires deep expertise in modern medicinal chemistry, including structure-based design, SAR optimization, and integration of ADME/PK and safety considerations, along with a strong understanding of the interdisciplinary drug discovery process. The candidate will collaborate closely with biology, DMPK, and toxicology teams and may lead cross-functional project efforts.