Senior Dir, In-Vivo & Non-Clinical Pharmacology

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Role Overview

Bristol Myers Squibb is seeking a strategic and scientifically grounded leader to serve as the Senior Director for In-Vivo & Non-Clinical Pharmacology. This leader will partner deeply with Research leadership and the Pharmacology, DMPK, Toxicology, and Translational Science units to deliver the applications, workflow capabilities, AI, and supporting data flows that enable non-clinical decisions across in-vivo biology, DMPK, ADME, non-clinical safety, toxicology, and bioanalytical science.

The role is focused on the digital and analytical capability layer that helps Research generate, interpret, and act on non-clinical evidence, rather than owning the underlying scientific operations themselves. In close partnership with BMS’s R&D Data organization and peer BI&T leaders, this role will help build an integrated, multi-year environment in which non-clinical evidence flows cleanly into translational, clinical pharmacology, regulatory, and Development decision-making.

Reporting to the Vice President, Research Business Insights & Technology, this leader will operate as part of a unified BI&T leadership team and act as a trusted partner to Research leadership, translating scientific needs into scalable, integrated technology solutions.

Mission & Impact

• Enable higher-confidence candidate progression decisions through integrated non-clinical applications, AI, and workflow support
• Modernize PK/PD, DMPK/ADME, toxicology, and bioanalytical decision environments with predictive and AI-enabled capabilities
• Improve how non-clinical evidence is captured, connected, and reused to support downstream translational, clinical pharmacology, regulatory, and Development decisions
• Advance predictive safety, translational modeling support, histopathology image AI, and agent-enabled study workflows where they create clear scientific value
• Reduce fragmentation across non-clinical workflows and improve decision speed, traceability, and reuse of evidence

Key Responsibilities

• Partner with Pharmacology, DMPK, Toxicology, and Translational Science leaders to shape and deliver the technology roadmap supporting non-clinical decisions
• Lead deployment of GenAI, agentic, and predictive AI/ML capabilities for non-clinical workflows, including predictive safety, in silico DMPK, histopathology image AI, and study design support
• Ensure non-clinical data is captured with high fidelity in source systems and flows cleanly to downstream curation by the R&D Data organization
• Partner with scientific, quality, and operational stakeholders to ensure applications appropriately support animal welfare data, IACUC-related processes, and study-governance workflows
• Enable non-clinical safety signal detection and risk characterization through modern analytics, integrated data flows, and decision-support tools
• Partner with Development teams so that clinical findings flow back into non-clinical model validation and refinement
• Ensure operational excellence and reliability of non-clinical applications, modeling environments, and analytics
• Lead and develop a team of scientific technologists, AI/ML engineers, product leaders, and application specialists

Required Experience & Qualifications

• Bachelor’s, Master’s, or Ph.D. in Pharmacology, Pharmaceutical Sciences, Biology, Bioinformatics, or related field (Ph.D. preferred)
• 12–15+ years in pharmaceutical R&D with strong exposure to preclinical and translational science
• Deep understanding of in-vivo pharmacology, DMPK/ADME, safety/toxicology, and bioanalytical workflows
• Proven experience leading applications, digital products, or AI-enabled capabilities in non-clinical R&D, including predictive safety, in silico DMPK, or histopathology image AI
• Experience working in GLP-adjacent regulated environments and with IACUC-related processes
• Proven leadership at Director or Senior Director level

Critical Capabilities

• Scientific Depth in Non-Clinical Pharmacology — Engages deeply with non-clinical scientific leaders and understands experimental design, data, and interpretation
• Strategic Partnership — Acts as a trusted partner to Research leadership, translating scientific needs into integrated technology solutions
• AI / Predictive Modeling Strategy — Fluent in predictive safety, in silico DMPK, image AI, and agentic capabilities for non-clinical workflows
• Regulated Workflow Fluency — Fluent with GLP, IACUC, and non-clinical safety governance
• End-to-End Pipeline Thinking — Understands how non-clinical data impacts downstream Development and decision-making

Leadership & Change Attributes

• Strong ability to partner with senior scientific leaders and act as a trusted advisor
• Proven experience driving organizational and technology transformation in scientific environments
• Ability to translate complex scientific and technical concepts into actionable strategies
• Experience navigating matrixed, global organizations
• Commitment to building a high-performing, collaborative team culture

What Differentiates Top Candidates

• Experience leading non-clinical pharmaceutical sciences digital, AI, or application transformation initiatives
• Demonstrated success building integrated applications that support AI/ML-driven non-clinical workflows, including predictive safety, image AI, or in silico DMPK
• Background spanning bench science, computational methods, AI/ML, and enterprise applications
• Track record of improving how non-clinical evidence is connected, interpreted, and used in candidate decisions
• Demonstrated success integrating fragmented tool ecosystems into unified platforms 
• Credibility with both internal R&D leaders and external innovation partners 

Why This Role Matters Now

Bristol Myers Squibb is at a pivotal moment in reimagining how technology and AI support scientific discovery. Non-clinical pharmacology generates the evidence that determines which candidates enter humans, and this role matters now because scientists need better integrated applications, AI, and workflows to generate, interpret, and act on that evidence with greater speed and confidence. Done well, this capability becomes a strategic asset that improves candidate decisions and increases the probability of success across the pipeline.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Brisbane - CA - US: $252,640 - $306,137
Cambridge Crossing: $252,640 - $306,137
Princeton - NJ - US: $229,670 - $278,306
San Diego - CA - US: $252,640 - $306,137

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. 

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.
 

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental, and vision care.

• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).

• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

​Work-life benefits include:

Paid Time Off

• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)

• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

*Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at [email protected]. Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.

R1602983 : Senior Dir, In-Vivo & Non-Clinical Pharmacology