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Research Associate - Comprehensive Cancer Center

Columbus CampusPosted Yesterday
Full-timeonsite

Job Description

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Job Title:

Research Associate - Comprehensive Cancer Center

Department:

Medicine | School Biomedical Sciences Microbial Infection and Immunity

The Researcher 1 will support the laboratory of Dr. Xue Han, Assistant Professor in Microbial Infection & Immunity and member of the OSUCCC–James Translational Therapeutics Program. Dr. Han’s research centers on identifying novel immunomodulatory pathways, particularly the immune checkpoint molecule PD1H (VISTA), to understand mechanisms of immune escape in solid tumors and hematologic malignancies, improve anticancer immunity, and address immune-related adverse events from immunotherapy.

The Researcher 1 will participate in planning, executing, and analyzing laboratory studies using molecular and cellular techniques. This role directly supports projects investigating tumorinfiltrating immune cells, immunosuppressive signaling, and the development of therapeutic strategies targeting PD1H/VISTA for cancers such as acute myeloid leukemia (AML), glioblastoma, and other tumors.

Additional Information:

Key Responsibilities

  • Conduct experimental work supporting studies of immune checkpoint pathways (e.g., PD‑1H/VISTA) using molecular biology, flow cytometry, tissue culture, PCR, and immunohistochemistry.

  • Collect, analyze, and interpret immunology and cancer biology datasets, including those assessing T‑cell activation, tumor immune evasion, and immunosuppressive signaling. Assist in developing and optimizing new methodologies.

  • Perform literature reviews in tumor immunology, immune checkpoints, AML, glioma, and immunotherapy; and contribute to manuscripts, grant proposals, and research presentations.

  • Support lab safety and compliance, ensuring adherence to institutional and federal research guidelines.

  • Assist in daily lab operations, including equipment maintenance, ordering supplies, and training students or staff on experimental techniques.

  • Perform additional duties to support ongoing research needs within the Han Lab.

Required Qualifications

  • Bachelor’s degree in biological or health sciences or equivalent experience.
  • Ability to translate and apply academic knowledge in biological/health science research.
  • Experience in a research capacity preferred.

Strong analytical and communication skills.

Location:

Pelotonia Research Center (1040)

Position Type:

Regular

Scheduled Hours:

40

Shift:

First Shift

Final candidates are subject to successful completion of a background check.  A drug screen or physical may be required during the post offer process.

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The university is an equal opportunity employer, including veterans and disability. 

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