Browse Jobs
Browse fresh roles from company career pages, then filter by keyword, location, salary, skills, remote scope, and more. Each listing links back to the employer-controlled apply path when available.
143 jobs match your filters
1mo
Information System Security Officer (ISSO) - DHS
LMI
LMI is seeking an Information System Security Officer (ISSO) to support our Department of Homeland Security (DHS) market. LMI is a new breed of digital solutions provider dedicated to accelerating government impact with innovation and speed. Investing in technology and prototype
Remote, US
remote
1mo
Information System Security Officer (ISSO), Senior (On-Prem & Cloud)
AMERICAN SYSTEMS
AMERICAN SYSTEMS is seeking a Senior Information System Security Officer (ISSO) to manage RMF execution, authorization, and continuous monitoring for hybrid on‑premises and cloud systems supporting classified government missions in Chantilly, VA. This role is ideally suited for
Chantilly, VA, US
hybridFull-time
3d
R
Senior Information System Security Officer (ISSO) - Andover, MA
RTX
Date Posted: 2026-06-15

 Country: United States of America Location: US-MA-ANDOVER-AN1 ~ 350 Lowell St ~ AN1 ESSEX BLDG Position Role Type: Onsite U.S. Citizen, U.S. Person, or Immigration Status Requirements: Active and transferable U.S. government issued security clea
US-MA-ANDOVER-AN1 ~ 350 Lowell St ~ AN1 ESSEX BLDG
onsiteFull-time
6d
Cybersecurity – Information System Security Officer (ISSO)
Hatch
Cybersecurity – Information System Security Officer (ISSO) Company: The Boeing Company The Boeing Company is looking for a highly motivated Cybersecurity – Information System Security Officer (ISSO) to join our Classified Operations Cybersecurity team based in Hazelwood, MO. Th
USA - Hazelwood, MO
onsiteFull-time
6d
B
Cybersecurity – Information System Security Officer (ISSO)
Boeing
Cybersecurity – Information System Security Officer (ISSO) Company: The Boeing Company The Boeing Company is looking for a highly motivated Cybersecurity – Information System Security Officer (ISSO) to join our Classified Operations Cybersecurity team based in Hazelwood, MO. Th
USA - Hazelwood, MO
onsiteFull-time
6d
Cybersecurity – Information System Security Officer (ISSO)
Millennium Space Systems
Cybersecurity – Information System Security Officer (ISSO) Company: The Boeing Company The Boeing Company is looking for a highly motivated Cybersecurity – Information System Security Officer (ISSO) to join our Classified Operations Cybersecurity team based in Hazelwood, MO. Th
USA - Hazelwood, MO
onsiteFull-time
1w
C
Senior Information System Security Officer
CACI
Job Title: Senior Information System Security Officer Job Category: Information Technology Time Type: Full time Minimum Clearance Required to Start: Secret Employee Type: Regular Percentage of Travel Required: Up to 10% Type of Travel: Local * * * The Opportunity: CACI is searchi
Washington, DC, US
remote
1w
C
Senior Information System Security Officer
CACI
Job Title: Senior Information System Security Officer Job Category: Information Technology Time Type: Full time Minimum Clearance Required to Start: Secret Employee Type: Regular Percentage of Travel Required: Up to 10% Type of Travel: Local * * * The Opportunity: CACI i
Washington, DC, US
remoteFull-time
1w
DHS Information System Security Officer II
OneZero Solutions
We are an employee-centric company that truly appreciates our team members and their value to our customers and the missions they support. We pride ourselves on being forward-leaning thinkers and fostering teams that are and continue to be technically proficient and technically c
Washington, DC, 20001, US
onsiteFull-time
1w
R
eWAN Information System Security Officer (ISSO) (Onsite)
RTX
Date Posted: 2026-06-10

 Country: United States of America Location: US-MA-TEWKSBURY-TB1 ~ 50 Apple Hill Dr ~ ASSABET BLDG Position Role Type: Onsite U.S. Citizen, U.S. Person, or Immigration Status Requirements: Active and transferable U.S. government issued security c
US-MA-TEWKSBURY-TB1 ~ 50 Apple Hill Dr ~ ASSABET BLDG
onsiteFull-time
1w
R
Senior Information System Security Officer (ISSO) - Tucson, AZ
RTX
Date Posted: 2026-06-10

 Country: United States of America Location: US-AZ-TUCSON-808 ~ 1151 E Hermans Rd ~ BLDG 808 Position Role Type: Onsite U.S. Citizen, U.S. Person, or Immigration Status Requirements: Active and transferable U.S. government issued security clearan
US-AZ-TUCSON-808 ~ 1151 E Hermans Rd ~ BLDG 808
onsiteFull-time
1w
C
Senior Information System Security Officer
CACI
Job Title: Senior Information System Security Officer Job Category: Information Technology Time Type: Full time Minimum Clearance Required to Start: TS/SCI Employee Type: Regular Percentage of Travel Required: None Type of Travel: None * * * The Opportunity: CACI is searching for
NATIONAL HARBOR, MD, US
hybrid
1w
C
Senior Information System Security Officer
CACI
Job Title: Senior Information System Security Officer Job Category: Information Technology Time Type: Full time Minimum Clearance Required to Start: TS/SCI Employee Type: Regular Percentage of Travel Required: None Type of Travel: None * * * The Opportunity: CACI is searc
NATIONAL HARBOR, MD, US
hybridFull-time
2w
Senior Information System Security Officer (ISSO)
Alpha Omega
Job Title: Senior Information System Security Officer (ISSO) Clearance Required: Public Trust, US Citizen; Work Location: Remote.
Vienna, VA, United States
hybridFull-time
2w
R
Senior Information System Security Officer (ISSO) - Tucson, AZ
RTX
Date Posted: 2026-06-02

 Country: United States of America Location: US-AZ-TUCSON-M05 ~ 1151 E Hermans Rd ~ BLDG M05 (External Site) Position Role Type: Onsite U.S. Citizen, U.S. Person, or Immigration Status Requirements: Active and transferable U.S. government issued
US-AZ-TUCSON-M05 ~ 1151 E Hermans Rd ~ BLDG M05 (External Site)
onsiteFull-time
2w
R
Senior Information System Security Officer (ISSO) - El Segundo, CA
RTX
Date Posted: 2026-06-01

 Country: United States of America Location: US-CA-EL SEGUNDO-E04 ~ 2006 E El Segundo Blvd ~ BLDG E04 Position Role Type: Onsite U.S. Citizen, U.S. Person, or Immigration Status Requirements: Active and transferable U.S. government issued securit
US-CA-EL SEGUNDO-E04 ~ 2006 E El Segundo Blvd ~ BLDG E04
onsiteFull-time
2w
R
Senior Information System Security Officer (ISSO) - Tucson, AZ
RTX
Date Posted: 2026-06-01

 Country: United States of America Location: US-AZ-TUCSON-M05 ~ 1151 E Hermans Rd ~ BLDG M05 (External Site) Position Role Type: Onsite U.S. Citizen, U.S. Person, or Immigration Status Requirements: Active and transferable U.S. government issued
US-AZ-TUCSON-M05 ~ 1151 E Hermans Rd ~ BLDG M05 (External Site)
onsiteFull-time
2w
R
Senior Information System Security Officer (ISSO) - Marlborough, MA
RTX
Date Posted: 2026-06-01

 Country: United States of America Location: US-MA-MARLBOROUGH-MA2 ~ 1001 Boston Post Rd ~ BLDG 2 Position Role Type: Onsite U.S. Citizen, U.S. Person, or Immigration Status Requirements: Active and transferable U.S. government issued security cl
US-MA-MARLBOROUGH-MA2 ~ 1001 Boston Post Rd ~ BLDG 2
onsiteFull-time
2w
C
Intermediate Information System Security Officer
CACI
Job Title: Intermediate Information System Security Officer Job Category: Information Technology Time Type: Full time Minimum Clearance Required to Start: Top Secret Employee Type: Regular Percentage of Travel Required: Up to 10% Type of Travel: Local * * * The Opportunity: CACI
Washington, DC, US
remote
1mo
R
Senior Information System Security Officer (ISSO) - Tewksbury, MA
RTX
Date Posted: 2026-05-19 Country: United States of America Location: US-MA-TEWKSBURY-TB3 ~ 50 Apple Hill Dr ~ CONCORD BLDG, Tewksbury Tb3 300 Concord Position Role Type: Onsite U.S. Citizen, U.S. Person, or Immigration Status Requirements: Active and transferable U.S. government
US-MA-TEWKSBURY-TB3 ~ 50 Apple Hill Dr ~ CONCORD BLDG, Tewksbury Tb3 300 Concord
onsiteFull-time
1mo
L
Senior Information System Security Officer
Leidos
Leidos has a new and exciting opportunity for a Senior Information System Security Officer in our National Security Sector's (NSS) Cyber & Analytics Business Area (CABA). Our talented team is at the forefront in Security Engineering, Computer Network Operations (CNO), Mission So
Annapolis Junction, MD
onsiteFull-time
1mo
R
SkillBridge Intern DoD: Information System Security Officer - Forest, MS
RTX
Date Posted: 2026-05-07 Country: United States of America Location: US-MS-FOREST-425 ~ 19859 Hwy 80 ~ BLDG 425 Position Role Type: Onsite U.S. Citizen, U.S. Person, or Immigration Status Requirements: Active and transferable U.S. government issued security clearance is required
US-MS-FOREST-425 ~ 19859 Hwy 80 ~ BLDG 425
onsiteFull-time
1mo
R
SkillBridge Intern DoD: Information System Security Officer - McKinney, Texas
RTX
Date Posted: 2026-05-07 Country: United States of America Location: US-TX-MCKINNEY-513WA ~ 2501 W University Dr ~ WING A BLDG Position Role Type: Onsite U.S. Citizen, U.S. Person, or Immigration Status Requirements: Active and transferable U.S. government issued security clearan
US-TX-MCKINNEY-513WA ~ 2501 W University Dr ~ WING A BLDG
onsiteFull-time
1mo
Senior Information System Security Officer
Core One
Join our team at Core One! Our mission is to be at the forefront of devising analytical, operational and technical solutions to our Nation's most complex national security challenges. In order to achieve our mission, Core One values people first! We are committed to recruiting, n
McLean, VA
onsiteEasy Apply
1mo
R
SkillBridge Intern DoD: Information System Security Officer - Tucson, AZ
RTX
Date Posted: 2026-04-24 Country: United States of America Location: US-AZ-TUCSON-M05 ~ 1151 E Hermans Rd ~ BLDG M05 (External Site) Position Role Type: Onsite U.S. Citizen, U.S. Person, or Immigration Status Requirements: Active and transferable U.S. government issued security c
US-AZ-TUCSON-M05 ~ 1151 E Hermans Rd ~ BLDG M05 (External Site)
onsiteFull-time