Director/Sr. Director, Oligonucleotide Translational Science

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Director/Sr. Director, Oligonucleotide Translational Science based in United States.

This is a high-impact translational science leadership opportunity at the forefront of oligonucleotide therapeutics for genetic diseases. The role sits at the critical intersection of preclinical pharmacology, DMPK, safety, and IND-enabling strategy, with direct influence on how programs advance from discovery into clinical development. You will act as a scientific integrator, translating complex in vivo and in vitro datasets into coherent development narratives that guide candidate selection, regulatory readiness, and portfolio decisions. Working closely with cross-functional teams in chemistry, toxicology, DMPK, and translational biology, you will help define what data is needed for IND success and ensure execution is rigorous and efficient. This is a highly visible role where scientific leadership, hands-on expertise, and strategic thinking directly shape program direction and patient impact.

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Director/Sr. Director, Oligonucleotide Translational Science based in United States.

This is a high-impact translational science leadership opportunity at the forefront of oligonucleotide therapeutics for genetic diseases. The role sits at the critical intersection of preclinical pharmacology, DMPK, safety, and IND-enabling strategy, with direct influence on how programs advance from discovery into clinical development. You will act as a scientific integrator, translating complex in vivo and in vitro datasets into coherent development narratives that guide candidate selection, regulatory readiness, and portfolio decisions. Working closely with cross-functional teams in chemistry, toxicology, DMPK, and translational biology, you will help define what data is needed for IND success and ensure execution is rigorous and efficient. This is a highly visible role where scientific leadership, hands-on expertise, and strategic thinking directly shape program direction and patient impact.

We use an AI-powered matching process to ensure your application is reviewed quickly, objectively, and fairly against the role's core requirements. Our system identifies the top-fitting candidates, and this shortlist is then shared directly with the hiring company. The final decision and next steps (interviews, assessments) are managed by their internal team.

We appreciate your interest and wish you the best!

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