Clinical Research Nurse II

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Overview
The Clinical Research Nurse II (CRN2) will be responsible for providing clinical and research services to patients participating in multiple projects within Yale Clinical and Community Research.

The CRN2 will provide support for a hepatitis C testing and rapid start research project. The project is based at Yale School of Medicine, with 4 additional sites throughout Connecticut, with occasional travel to sites possible. The CRN2 will also participate in an HIV/HCV surveillance project in the New Haven Syringe Services Program. In addition, the CRN2 will provide mobile care, clinical outreach and care coordination, and harm reduction services for the Community Health Care Van and New Haven Syringe Services Program (including but not limited to, injections, vaccinations, medication administration, wound care, STI testing, overdose prevention counseling).

In each of these projects, the CRN2 participates in the design, administration, and monitoring of clinical and social behavioral research projects. The CRN2 conducts clinical research on study subjects by providing nursing services in compliance with relevant guidelines.

Key responsibilities include patient recruitment and data collection, providing point of care testing and phlebotomy services, following clinical protocols for study subjects (including follow-up on orders from prescribing providers, administration of injections, physical assessments, treatment and medication adherence activities, patient education, and triaging patients). The role involves evaluating subjects for study inclusion, obtaining informed consent, coordinating patient care, managing study protocols, and collaborating with multidisciplinary researchers. The CRN2 conducts study assessments and visits using standardized data collection tools. The CRN2 develops study subject referral sources; designs and develops outreach programs.

The CRN2 will participate in developing procedures, quality assurance standards, and ensuring regulatory compliance. The CRN2 will also participate in analyzing and evaluating clinical data gathered to ensure compliance with protocol and overall clinical objective, maintaining regulatory compliance, and ensuring accurate data and biospecimen collection. Additionally, the position provides team support on research projects, ensuring meticulous data management, and assisting in the preparation of reports and publications.

The CRN2 adheres to all human subjects regulations as defined by Yale University and the federal government that pertain to research studies. The CRN2 also participates in research activities: Contributes to HIC/IRB submissions. Based on knowledge of science and research goals, collaborates with PIs on major revisions and contributes to scientific protocols. Plans and implements changes. Develops forms, clinical questionnaires and the application of research techniques; contributes to procedures manuals for clinical protocols and data collection. Responsible for the documentation of study data in EPIC and other study databases. Reviews Electronic Health Records for relevant clinical history and information. Documents clinical information as needed in the EHR (point of care test results, procedures, nursing notes). Ensures that report forms are accurately documented and completed in a timely manner at each site location.

The CRN2 delegates tasks and supervises the activities of other licensed and unlicensed care providers. May perform other duties as assigned for the Community Health Care Van and New Haven Syringe Services program (harm reduction materials distribution and collection, Narcan training, vending machine stock management, etc.).

Required Skills and Abilities
1. Excellent clinical, analytical, and organizational skills with demonstrated research nursing ability. Demonstrated ability to evaluate subject suitability, coordinate patient enrollment, and obtain informed consent.

2. At least 3 years of experience as a Registered Nurse.

3. Proven ability to multi-task, maintain confidentiality and remain focused in a fast-paced environment. Excellent time management and organizational skills. Strong organizational and time management skills, with the ability to manage multiple research studies simultaneously.

4. Excellent written and verbal communication skills with strong attention to detail, for interacting with study participants and medical teams.

5. Proficiency in Microsoft Office Suite, and electronic health records (EPIC).

Preferred Skills and Abilities
1. Proven experience conducting and supporting all phases of clinical research, including recruitment, data management, and analysis.

2. Previous experience working on large-scale research studies or multi-site projects.

3. Proficiency in using electronic medical records and research databases.

4. Demonstrated knowledge of Connecticut community resources.

5. Proficiency in using electronic medical records and research databases.

6. Experience with phlebotomy and wound care for patients who use injection drugs

7. Experience with people with serious mental illness, homelessness, substance use and people with HIV and/or hepatitis C risk or in treatment.

Principal Responsibilities

1. Evaluates and assesses subject’s suitability for inclusion in studies; develops and modifies procedures according to study findings; recommends changes to the study protocol to coincide with study goals and objectives. 2. Develops and implements procedures and data quality assurance standards for safety monitoring components of studies. 3. Contributes to designing activities, policies and procedures to improve day to day efficiency of the recruitment and assessment components of the study and to ensure that staff members perform activities within established research protocol. 4. Arranges patient enrollment, determines patient eligibility and obtains informed consent. 5. Develops study subject referral sources; designs and develops outreach programs. 6. Collaborates with multidisciplinary researchers to coordinate research programs that integrate new advances in clinical trials. 7. Delegates tasks and supervises the activities of other licensed and unlicensed care providers. 8. May perform other duties as assigned. Required Education and Experience Bachelor’s of Science Degree in Nursing and four years of related experience or an equivalent combination of education and experience. Required License(s) or Certification(s) Licensure as Registered Nurse in the State of Connecticut or Connecticut license eligible.

Job Posting Date

05/06/2026

Job Category

Professional

Bargaining Unit

NON

Compensation Grade

Clinical & Research

Compensation Grade Profile

Clinical Research Nurse 2 (24)

Salary Range

$68,000.00 - $120,500.00

Time Type

Full time

Duration Type

Staff Fixed Duration (Fixed Term)

Work Model

On-site

Background Check Requirements

All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. For additional information on the background check requirements and process visit "Learn about background checks" under the Applicant Support Resources section of Careers on the It's Your Yale website.

Health Requirements

Certain positions have associated health requirements based on specific job responsibilities. These may include vaccinations, tests, or examinations, as required by law, regulation, or university policy.

Posting Disclaimer

Salary offers are determined by a candidate’s qualifications, experience, skills, and education in relation to the position requirements, along with the role’s grade profile and current internal and external market conditions.

The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the position. Employees will be assigned specific job-related duties through their hiring department.

The University is committed to basing judgments concerning the admission, education, and employment of individuals upon their qualifications and abilities and seeks to attract to its faculty, staff, and student body qualified persons from a broad range of backgrounds and perspectives. In accordance with this policy and as delineated by federal and Connecticut law, Yale does not discriminate in admissions, educational programs, or employment against any individual on account of that individual’s sex, sexual orientation, gender identity or expression, race, color, national or ethnic origin, religion, age, disability, status as a special disabled veteran, veteran of the Vietnam era or other covered veteran.

Inquiries concerning Yale's Policy Against Discrimination and Harassment may be referred to the Office of Institutional Equity and Accessibility (OIEA).

Note

Yale University is a tobacco-free campus.