Research Technician II

Site: The General Hospital Corporation

 

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

 

Job Summary

The Grabowski Laboratory is looking for a pre-medical student interested in translational research, or for a young investigator who seeks a medical research career to fill a position as a Research Technician II. The person in this job will carry out research on two major clinical problems: 1) the further development of a first effective therapy for a devastating thrombotic microangiopathy known as the childhood hemolytic uremic syndrome (eHUS), and 2) the study of von Willebrand Disease, the most common inherited bleeding disorder. Work for 2) encompasses laboratory microfluidics and biochemistry combined with clinical bleeding assessments and the obtaining of informed consent for research trials. We are presently examining the little understood role of the von Willebrand factor (VWF) pro-peptide in bleeding and clotting, and the function of VWF as an anti-angiogenic factor that, when deficient, may lead to unregulated angiogenesis and increased bleeding from fragile blood vessels in mucous membranes. Work for 1) involves the pursuit of novel therapeutic targets for eHUS by means of a genetically modified mouse model and an all-human endothelial cell culture model. The laboratory utilizes cell cultures of human endothelial cells, ELISAs for clotting factor activities, controlled hemodynamics of blood flow, fluorescence digital video-microscopy, real-time digital image processing (e.g., antigen co-localization) using a state-of-the-art imaging system, an ex vivo flow chamber to simulate flow in arteries, human arterioles, and MetaMorph Premier digital imaging software. This is a great opportunity for, as stated above, either a pre-medical student interested in translational research, or for a young investigator who seeks a medical research career. The lab director is a senior pediatric hematologist and an experienced scientist. Also overseeing the translational work is a senior medical hematologist. An applicant for this position should have a background in biology, chemistry, or a related other medical science.

Summary
Carries out a broad range of technically advanced research activities and procedures; evaluates conclusions and has considerable latitude to modify or devise methods and techniques as necessary to achieve desired results; typically supervises technical and sometimes administrative elements of the research unit.

Does this position require Patient Care?
No

Essential Functions
-Executes protocols of non-routine experiments.
-Assists PI with determining the most suitable methodology.
-Performs basic design and modification of protocols.
-Calculates, transcribes, and analyzes data.
-Prepares and presents reports.
-Organizes and summarizes acquired data using scientific and Statistical Techniques.
-Participates in the design of experiments or field work.

 

Education
Bachelor's Degree Related Field of Study required

Can this role accept experience in lieu of a degree?
Yes

Licenses and Credentials

Experience
Previous Research Lab Experience 1-2 years required

Knowledge, Skills and Abilities
- Analytical skills and ability to resolve technical problems.
- Ability to interpret acceptability of data results.
- Strong Computer skills.
- Demonstrated competence in research techniques and methodologies.

 

 

Hybrid

 

55 Fruit Street

 

40

 

Regular

 

Day (United States of America)

 

Pay Range

$24.28 - $39.43/Hourly

 

Grade

6

 

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

 

1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

 

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