Senior Director, US Commercial Supply Lead

At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.

Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.

Does this inspire you and feel like a fit? Then we would love to have you join us!

The Sr. Director, US Supply Chain Lead is pivotal in ensuring that innovative therapies reach patients across the US without interruption. As a senior leader, you will shape how supply chain strategy enables commercial success and patient impact at scale.

This role is a key member of the broader Global Supply Chain leadership team and acts as a strategic partner to the US Commercial Leadership team. The role also serves as a key escalation point for supply, distribution, and process issues impacting market performance, customer service, and compliance.

Responsibilities

• You will be responsible for defining and leading the US commercial supply chain strategy aligned with corporate objectives and portfolio priorities, including long-term distribution and channel strategies that support evolving market access models and patient needs.

• You will serve as the US Supply Chain voice in the Global S&OP process, influencing decisions on inventory and capacity. You will facilitate forecasting and demand management for the US market by establishing robust demand review processes, aligning forecast assumptions with commercial input, and improving forecast accuracy to support reliable supply, inventory management, and financial planning.

• You will collaborate closely with Finance on forecasting assumptions, inventory implications, accrual-relevant inputs, budget alignment, and performance follow-up to ensure operational decisions are financially sound and transparent.

• You will act as a strategic partner to US Commercial Leadership, including Sales, Marketing, Market Access, and Patient Services. You will translate commercial strategy, demand signals, and market events into actionable supply chain plans and provide executive-level insights on supply risks, trade-offs, and scenario planning.

• You will define and optimize the US distribution network strategy, including 3PLs, wholesalers, specialty distributors, and specialty pharmacies. You will partner closely with Trade to align operational execution with market requirements, channel dynamics, distribution models, and customer needs.

• You will drive supply chain strategy and readiness for US product launches, indications, and lifecycle expansions. This includes close collaboration with the Corporate Supply Chain Lifecycle Management team to ensure timely launches and delivery to markets, as well as overseeing launch governance and cross-functional alignment at the executive level.

• You will own US market product availability, service levels, OTIF performance, and inventory performance. You will act as the escalation point for critical supply, service, compliance, and distribution issues impacting the US market and lead cross-functional risk assessment, scenario planning, and mitigation to protect product availability and customer service.

• You will ensure full compliance with DSCSA, GDP, and all applicable US regulatory requirements. You will work with Quality Assurance to maintain GxP compliance throughout the supply chain network, including exception handling, root cause investigations, CAPA implementation and closure, QMR reporting, and KPI maintenance.

• You may also be assigned other job duties from time to time.

Requirements

Moreover, you meet the following professional requirements:

• Bachelor’s degree in Supply Chain, Engineering, Life Sciences, or a related field; MBA or advanced degree strongly preferred

• 12–15+ years of progressive supply chain experience in biopharma or life sciences

• Significant experience leading US commercial supply chains, including product launches

• Demonstrated leadership experience in US commercial operations

• Deep knowledge of US pharmaceutical distribution models, including wholesalers, specialty pharmacies, and 3PL networks

• Strong understanding of S&OP / IBP processes, demand planning, inventory management, and supply network strategy

• Extensive experience operating within GMP/GDP and DSCSA-regulated environments

• Experience working cross-functionally with Trade, Finance, Quality, and Commercial stakeholders

• Proven ability to lead through complexity, influence senior stakeholders, and drive performance across internal teams and external partners

• Track record of successful multi-product or global launch execution

• Experience with advanced planning systems, such as SAP and Anaplan

• Prior experience in both global and US-focused roles

• Ability to assess operational, financial, and compliance implications across multiple courses of action and determine the most appropriate path forward

• Strong judgment in escalation management, partner oversight, risk mitigation, and prioritization in a fast-changing commercial environment

• Strong communication skills, both oral and written

For US based candidates, the proposed salary band for this position is as follows:

$235,440.00---$353,160.00

The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as discretionary bonuses and long-term incentives. 

When you join Genmab, you’re joining a culture that supports your physical, financial, social, and emotional wellness. Within the first year, regular full-time U.S. employees are eligible for:

• 401(k) Plan: 100% match on the first 6% of contributions

• Health Benefits: Two medical plan options (including HDHP with HSA), dental, and vision insurance

• Voluntary Plans: Critical illness, accident, and hospital indemnity insurance

• Time Off: Paid vacation, sick leave, holidays, and 12 weeks of discretionary paid parental leave

• Support Resources: Access to child and adult backup care, family support programs, financial wellness tools, and emotional well-being support

• Additional Perks: Commuter benefits, tuition reimbursement, and a Lifestyle Spending Account for wellness and personal expenses 

About You

• You are genuinely passionate about our purpose

• You bring precision and excellence to all that you do

• You believe in our rooted-in-science approach to problem-solving

• You are a generous collaborator who can work in teams with a broad spectrum of backgrounds

• You take pride in enabling the best work of others on the team

• You can grapple with the unknown and be innovative

• You have experience working in a fast-growing, dynamic company (or a strong desire to)

• You work hard and are not afraid to have a little fun while you do so!

Locations

Genmab maximizes the efficiency of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are crafted as open, community-based spaces that work to connect employees while being immersed in our powerful laboratories. Whether you’re in one of our office spaces or working remotely, we thrive on connecting with each other to innovate.

About Genmab

Genmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO®) antibody medicines.

Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on LinkedIn and X.

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Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.