Talent Business Partner - Human Resources

About Signant Health At Signant Health, we help bring life-changing treatments to patients faster. We are a global evidence generation company that supports clinical trials with smart technology, scientific expertise, and hands-on operational support — so better data leads to better decisions in healthcare. We embrace AI and advanced technologies to enhance every aspect of what we do, from data analysis to operational efficiency. Our teams work at the intersection of science, technology, and patient experience, delivering digital solutions powered by AI innovation that make clinical trials more efficient, more accurate, and more accessible around the world. Trusted by leading pharmaceutical companies and CROs, our platforms and services support studies across more than 90 countries and have contributed to hundreds of new drug approvals. If you are motivated by meaningful work, global impact, and innovation in clinical research and digital health — including the opportunity to work with cutting-edge AI technologies — you will find purpose and opportunity at Signant Health. About the Role: We are seeking an experienced Talent Business Partner (TBP) to serve as a strategic HR partner for our teams across South Africa. You will support multiple functions and provide dedicated local country-based support, while also partnering with our operations organizations and other functions as needed globally. This role will operate within a matrixed global HR structure as a strategic partner and change agent. You’ll build strong relationships with business leaders, employees, other TBPs, and HR Centers of Excellence in implementing integrated talent solutions that drive business success. What you will do: Strategic Business Partnering Provide dedicated local HR support for teams in South Africa and partner with leadership teams globally to align people strategies with business objectives. Support organizational design, workforce planning, and team effectiveness initiatives. Drive strategic people initiatives that enable business growth. Employee Relations & Talent Advisory Partner with specialist HR teams to deliver talent programs across compensation, rewards, learning & development, and more. Serve as a trusted advisor on performance management, talent development, organizational change, and succession planning. Address and resolve complex employee relations matters through thorough investigations, appropriate documentation, and sensitivity, escalating when necessary in collaboration with Legal and Employee Relations teams. Oversee employment termination processes in South Africa, ensuring accurate calculations and compliance with the Labor Relations Act (LRA), including substantive and procedural fairness requirements. Compliance & Legal Support Maintain and update internal workplace regulations in accordance with South African employment legislation, including the Basic Conditions of Employment Act (BCEA), Labor Relations Act (LRA), Employment Equity Act (EEA), and Skills Development Act (SDA). Partner with workplace safety (COIDA/Compensation Fund) and social security authorities in South Africa, and support Employment Equity reporting and compliance obligations. Coordinate labor inspections and respond to inquiries from labor authorities. Compensation, Benefits & Total Rewards Complete payroll processing by ensuring accuracy of employee information, managing PAYE calculations, and resolving payroll-related inquiries in accordance with SARS requirements. Ensure compliance with mandatory statutory contributions including PAYE, Unemployment Insurance Fund (UIF), and Skills Development Levy (SDL), and administer benefit requirements in accordance with South African law. Oversee supplementary benefits programs and allowances. Advise on local work regulations including workweek standards, overtime, leave entitlements, and parental leave policies. Communication, Engagement & Analytics Drive effective communication and change management across employee lifecycle initiatives. Provide HR metrics, analytics, and insights to guide talent-related decision making. Conduct and analyze exit interviews to inform retention strategies. Collaborate with HR Centers of Excellence and regional TBPs to share feedback, support policy alignment, and localize global programs. Promote a culture of accountability and continuous improvement. Preferred Qualifications: Bachelor’s degree in Human Resources, Business Administration, or related field (or equivalent experience). Strong knowledge of South African employment law (LRA, BCEA, EEA, SDA, COIDA), including compliance practices and CCMA proceedings. Demonstrated experience applying equal employment opportunity (EEO) principles and anti-discrimination legislation, including the Employment Equity Act (EEA), to promote fair and equitable workplace practices. Ability to utilize Company-issued and approved Artificial Intelligence (AI) tools to support productivity, efficiency, and quality of work, while maintaining accountability for all AI-generated outputs. Professional fluency in English (required for regional and global collaboration). 5+ years of progressive HR experience including employee relations, talent management, and business partnering. Experience managing HR operations in South Africa including but not limited to benefits administration, PAYE/UIF/SDL compliance, CCMA proceedings, labor relations, and regulatory compliance. Demonstrated ability to influence, coach, and partner with leaders at all levels in a matrixed environment. Analytical mindset with experience leveraging HR data to support strategic recommendations. Payroll processing experience. Desired Qualifications: HR experience in other Sub-Saharan African countries preferred; global HR experience a plus. Why Signant Health? At Signant Health, your work has real impact. Everything we build, support, and deliver helps advance clinical research and bring new treatments to patients faster — improving lives around the world. Our teams combine science, technology, and operational expertise to solve complex clinical trial challenges, and every role contributes to that mission. We offer a collaborative, global environment where you can grow your career while working alongside experts across clinical, technology, data, and operations, with opportunities to learn, take ownership, and drive meaningful innovation — not just maintain the status quo. If you are looking for purpose-driven work, smart colleagues, and the opportunity to help shape the future of clinical research and digital health, Signant Health is the place to do it.   #LI-CL1